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Smile Lines

For most of us, smile lines - also known as nasolabial folds - are nothing to smile about. These lines and creases run from the side of the nose to the corner of the mouth, and are the result of the loss of facial volume and skin elasticity as we age. They can make you look older, tired, or unhappy - even though you feel youthful inside. Fortunately, treatment with RADIESSE® Volumizing Filler can replenish youthful volume and stimulate collagen production in this area, minimizing the appearance of those pesky facial lines, wrinkles, and folds that mask our smiles. Best of all, results are clinically proven to last a year or more in many patients.1,2,3

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Results that keep getting better

RADIESSE Volumizing Filler is truly unique in that it both immediately restores volume and stimulates the production of natural collagen.1 Some injectable fillers may do one or the other, but with RADIESSE Volumizing Filler you get the best of both worlds; immediate results paired with the extended benefit of natural collagen stimulation.1 With RADIESSE Volumizing Filler, the results start out great and just keep getting better.

Why choose RADIESSE® Volumizing Filler?

Treatment with RADIESSE Volumizing Filler takes only a few minutes, so your smile lines can be softened during your lunch hour. RADIESSE Volumizing Filler can save you time and money with long-lasting results, making it the natural choice for nasolabial folds treatment.2,3 Now that's something to smile about!*

*Individual Results May Vary

To learn more about RADIESSE Volumizing Filler for the treatment of smile lines, find a provider in your area.


1 Berlin A, Hussain M, Goldberg D. (2008) Calcium Hydroxylapatite Filler (RADIESSE®) for Facial Rejuvenation: A Histologic and Immonohistochemical Analysis. Dermatologic Surgery, Volume 34, S64-S67.

2 Moers-Carpi M, Vogt S, et. Al (2007) A Multicenter, Randomized Trial Comparing Calcium Hydroxylapatite to Two Hyaluronic Acids for Treatment of Nasolabial Folds, Dermatologic Surgery, 33 (2S), 144s-151s.

3 Bass LS, Smith S, Busso M, McClaren M. (2010) Calcium Hydroxylapatite (RADIESSE) for Treatment of Nasolabial Folds: Long-Term Safety and Efficacy Results.

4 Moers-Carpi M, Tufet J. (2007) Calcium Hydroxylapatite versus Nonanimal Stabilized Hyaluronic Acid for the Correction of Nasolabial Folds: A 12-Month, Multicenter, Prospective, Randomized, Controlled, Split-Face Trial, Dermatologic Surgery, 2008; 34:210-215.


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