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Corners of the Mouth

The corners of the mouth, also known as the oral commissures, can turn downward as you age and lose volume below the mouth. This downturned appearance of the mouth can make you look like you are frowning or even mad. In addition, volume loss in this area often leads to the formation or the deepening of already-formed marionette lines.

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Immediate Volume Plus Collagen Growth

RADIESSE® Volumizing Filler is specially designed to provide long-lasting results while giving you back your own natural collagen - and the results are immediate.1,2,3 With millions of treatments worldwide, RADIESSE Volumizing Filler has a history of proven results, including:

Treatment with RADIESSE Volumizing Filler takes only a few minutes and provides long-lasting results.2,3 And best of all, you'll leave the office seeing your results instantly. With immediate correction, an FDA-approved option for comfort, and results that keep getting better, RADIESSE Volumizing Filler is the natural choice for wrinkle treatments.2,3

RADIESSE Volumizing Filler is indicated for the treatment of moderate to severe facial wrinkles and folds. Individual results may vary.

If you're ready to find out more about RADIESSE Volumizing Filler, find a provider in your area.


1 Berlin A, Hussain M, Goldberg D. (2008) Calcium Hydroxylapatite Filler (RADIESSE®) for Facial Rejuvenation: A Histologic and Immonohistochemical Analysis. Dermatologic Surgery, Volume 34, S64-S67.

2 Moers-Carpi M, Vogt S, et. Al (2007) A Multicenter, Randomized Trial Comparing Calcium Hydroxylapatite to Two Hyaluronic Acids for Treatment of Nasolabial Folds, Dermatologic Surgery, 33 (2S), 144s-151s.

3 Bass LS, Smith S, Busso M, McClaren M. (2010) Calcium Hydroxylapatite (RADIESSE) for Treatment of Nasolabial Folds: Long-Term Safety and Efficacy Results.

4 Moers-Carpi M, Tufet J. (2007) Calcium Hydroxylapatite versus Nonanimal Stabilized Hyaluronic Acid for the Correction of Nasolabial Folds: A 12-Month, Multicenter, Prospective, Randomized, Controlled, Split-Face Trial, Dermatologic Surgery, 2008; 34:210-215.


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time has taken away.

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